Economic analysis of different throughput scenarios and implementation strategies of computer-aided detection software as a screening and triage test for pulmonary TB.

BackgroundArtificial Intelligence (AI) systems have demonstrated potential in detecting tuberculosis (TB) associated abnormalities from chest X-ray (CXR) images.Thus, they might provide a solution to radiologist shortages in high TB burden countries.However, the cost of implementing computer-aided detection (CAD) software has thus far been understu

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Echocardiography in Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is a common disorder characterized by unexplained left ventricular hypertrophy.The disease can have different phenotypic expressions and can be genetic in nature with autosomal dominant Diffuser inheritance.It usually runs a benign course in the majority but can lead to heart failure, atrial fibrillation, and sudde

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Comparative rates of evolution in endosymbiotic nuclear genomes

Abstract Background The nucleomorphs associated with secondary plastids of cryptomonads and chlorarachniophytes are the sole examples of organelles with eukaryotic nuclear genomes.Although not as widespread as their prokaryotic equivalents in Diffuser mitochondria and plastids, nucleomorph genomes share similarities in terms of reduction and compac

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Design and validation of an open-source modular Microplate Photoirradiation System for high-throughput photobiology experiments.

Research in photobiology is currently limited by a lack of devices capable of delivering precise and tunable irradiation to cells in a high-throughput format.This limits researchers to using expensive commercially available or custom-built light sources which make it difficult to replicate, standardize, optimize, and scale experiments.Here we prese

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